An American Werewolf in London is a 1981 British-American horror comedy film, written and directed by John Landis. It stars David Naughton, Griffin Dunne, and Jenny Agutter.

The opening shots of the moors are near Hay Bluff, a mountain that straddles the Welsh border in Brecon Beacons National Park.
East Proctor is a small hamlet ten miles to the west of Hay Bluff called Crickadarn.
The interior of the "Slaughtered Lamb" was filmed in a pub called The Black Swan, Ockham, Surrey near Effingham.

Nurse Alex's flat is located on Coleherne Road, just off Redcliffe Square (SW10), Kensington near to Earl's Court.

The attack at the tube station was set in — and filmed at — Tottenham Court Road tube station .

The final sequence in the alleyway was filmed at Clink Street, London.

The scenes where David wakes up naked in the zoo were shot at London Zoo, Regent's Park.