The Nasdaq 100 soared 25% year-to-date in 2024, reflecting gains from AppLovin, MicroStrategy, Palantir, Nvidia, and Axon. Their performance was driven by AI, crypto, and public safety technology, and they show continued growth potential for 2025. AppLovin saw eightfold growth with its AI-driven ad tech. MicroStrategy benefited from favorable cryptocurrency trends by leveraging its massive Bitcoin holding. Nvidia remains essential in AI with its cutting-edge GPUs. Axon's AI tools for public safety and Palantir's expanding AI analytics highlight their role in booming sectors, as analysts predict further gains.