In Chapter 3 of "The Screwtape Letters" by C.S. Lewis, Screwtape advises his nephew, Wormwood, on how to exploit the relationship between the human patient and his mother. Screwtape emphasizes the importance of fostering daily annoyances and irritations to create lasting resentment and discord. He suggests subtle strategies for Wormwood to manipulate the patient's perceptions and interactions.

The chapter delves into the dynamics of familial conflict, showcasing how seemingly minor annoyances can be amplified to create significant relational strife, and how demonic influence can exploit these tensions to erode human connections and spiritual well-being.