Pablo Escobar was a small-time thug who became the most feared cocaine trafficker in the world. Backed up by an army of killers and informers he dominated the infamous Medellin cocaine cartel and turned the South American nation of Colombia into a living hell. Anyone who stood against him was bought off or killed. But one DEA agent was determined to bring Escobar's reign of terror to an end. Working with an elite force of Colombian police he smashed the drug king's empire and rid Colombia of his evil influence once and for all.

More powerful than Pablo Escobar and more ruthless than Al Capone, Joaquín Guzmán Loera AKA El Chapo is America's number one illegal drug supplier. For over a decade, several US law enforcement agencies have been chasing the elusive drug kingpin across Mexico. Now, the DEA, Homeland Security and the US Marshals combine forces with the Mexican Marines to take him down.