Good news for parents of kids with severe food allergies and asthma. ARS Pharmaceuticals has developed a system for delivery of lifesaving doses of epinephrine via a nasal spray. Named Neffy, the spray delivers a 2 mg dose of epinephrine to nasal linings where the drug is quickly and efficiently absorbed into the systemic circulation. The company tested the device on 600+ individuals and demonstrated comparable or better drug delivery with subsequent blood pressure elevations than an epipen type device without the need for an injection. Some members of the FDA’s Pulmonary-Allergy Drugs Advisory Committee which must grant final approval to the spray still feel that more data is needed. When that is obtained, expect final approval and clinical availability later this year for use by patients weighing more than 66 pounds.

https://medicalxpress.com/news/2023-05-fda-panel-nasal-spray-combat.html

#epinephrine #epipen #nasalspray #allergy #asthma