In its 10 years on the air, "Friends" featured some unbelievable A-list guest stars who came and went out of the six lives of the central (perk) characters. Even for big names like Brad Pitt, George Clooney, Julia Roberts, Christina Applegate, Bruce Willis and so many more, appearing on the beloved sitcom could be a “terrifying” experience. (Tom Selleck, for example, has admitted to being scared to death.) While Reese Witherspoon verified that she, too, was nervous about her 2000 guest appearance, she recalled the excitement of sitting on Central Perk’s orange couch, as well as having her mind blown by Joey Tribiani actor Matt LeBlanc.

Today, Reese Witherspoon stars and executive produces "The Morning Show" on Apple TV+ with Jennifer Aniston — with fans impatiently waiting for Season 3 to hit the 2023 TV schedule — but the two actresses first crossed paths a couple of decades ago, when Witherspoon played Rachel Green’s younger sister Jill on two episodes of "Friends." The "Your Place or Mine" star spoke on "Late Night with Seth Meyers" about what that was like, and told an envy-inducing story about meeting Matt LeBlanc.