Compound Found in Red Wine Could Treat Depression Good news for wine-lovers. A compound found in red wine could pave the way for new depression and anxiety treatments. Tests on mice showed resveratrol, which is found in the skin of grapes, blocked an enzyme that causes depressive and anxious behavior. The Neuropharmacology journal study suggests the compound could be an effective alternative to drugs. Resveratrol, a powerful antioxidant, also has anti-inflammatory properties. Dr. Ying Xu, Lead study author, via Daily Mail