. sábado 04/05/19
River Plate 0 - 2 Peñarol
Plaza Colonia 0 - 1 Rampla Juniors
Boston River 0 - 4 Liverpool
Nacional 4 - 0 Progreso
. domingo 05/05/19
Cerro 0 - 2 Defensor Sporting
Danubio 4 - 3 Juventud
Racing 2 - 4 Wanderers
Cerro Largo 2 - 0 Fénix