Klopp continues to rotate his goalkeepers with Loris Karius starting ahead of Simon Mignolet, while Sadio Mane, Philippe Coutinho, Mohamed Salah and Firmino all start together for the first time this season.

Spartak are without this season’s top scorer Quincy Promes who misses out with a calf injury, meaning Luiz Adriano leads the line as the lone striker. On-loan Chelsea midfielder Mario Pasalic starts in the middle of midfield, with Andrei Eschenko and Georgi Dzhikiya filling the wing-back roles.