Former Israeli president and Nobel laureate Shimon Peres is said to be in a grave condition in hospital.
The 93-year-old was taken into hospital after a major stroke two weeks ago.
His condition was improving until he had a severe setback on Tuesday, according to Israeli media.
A hospital spokesperson said his condition “was and remains serious, there is a real threat to his life.”
Peres, Israel’s most eminent elder statesman, was part of almost every major development from the country’s founding in 1948.
In a career spanning nearly 70 years, he served in a dozen cabinets and was twice a Labour prime minister.
He shared the Nobel Peace Prize with the late former prime minister Yitzhak Rabin and the late Palestinian leader Yasser Arafat for the interim Oslo peace accord.