In 2005, Isabelle Dinoire received the world’s first face transplant after losing her nose, chin, and lips to an attack by a dog. It was announced on Tuesday that Dinoire, 49, passed away on April 22.

In 2005, Isabelle Dinoire received the world’s first partial face transplant after losing her nose, chin, and lips to an attack by a dog. 

It was announced on Tuesday that Dinoire, age 49, passed away on April 22nd. 

The cause was unspecified, though it was revealed she had been ill for some time. 

While the initial procedure was largely successful, the woman did struggle with issues involving tissue rejection and the medications prescribed to diminish the risk of such an occurrence. 

The drugs put her at a high cancer risk level, and she had developed 2 different kinds.

The transplant she underwent over a decade ago was groundbreaking, and in the years since, more than 30 similar procedures have been performed.