When Republican candidates take the stage tonight at the University of Colorado in Boulder for their third debate, a few things will be different.
This is the first debate following a national poll that shows Ben Carson leading Donald Trump in support among Republican voters.
In recent days Trump has been attacking Ben Carson, whereas in the last two debates they kept it cordial and Carson didn't have much speaking time.
The third GOP presidential debate, hosted by CNBC, starts at 8 p.m Eastern.
Moderators include CNBC's Carly Quintanilla, Becky Quick and John Harwood.
Candidates will have to answer questions focused on jobs, taxes, the deficit and the health of the economy among other issues.