Presence of a persistent or recurrent dysphoric mood lasting four or more weeks and accompanied by four or more of the following symptoms;

* Concentration or memory difficulties
* Insomnia or sleep disturbances
* Tiredness or low energy levels
* Agitation/Irritability
* Worry
* Teariness
* Hypervigilence or Overvigilence
* A feeling of pessimism or hopelessness about the future
* Feelings of worthlessness and low self esteem

Mixed Anxiety Depression is treated most effectively though Cognitive Behavior Therapy (CBT), using strategies that work for both anxiety and depressive disorders. People are taught how to change their thinking and behavior to reduce their anxiety and depression symptoms.