The San Francisco Giants will open up an interleague series with the Chicago White Sox in a Major League Baseball game betting pick selection set for Tuesday night.

Start time from Chicago is scheduled for 8PM Eastern Time with national television coverage provided by the MLB Extra Innings channel.

The odds from the opening game of this interleague series have the road side San Francisco Giants favored by -125 odds with the return on the home underdog Chicago White Sox at +115 odds. The run total is lined at 8 runs.